General Information

  • ID:  hor000431
  • Uniprot ID:  NA
  • Protein name:  Allatostatin A
  • Gene name:  NA
  • Organism:  Carcinus maenas
  • Family:  Allatostatin family
  • Source:  Animal
  • Expression:  thoracic ganglia and pericardial organ
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  NA
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  NA

Sequence Information

  • Sequence:  ARPYAFGL
  • Length:  8
  • Propeptide:  NA
  • Signal peptide:  NA
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  NA
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:   NA
  • IC50:  NA
  • EC50:  NA
  • ED50:  NA
  • Kd:  NA
  • Half life:  16.5 minutes; /990 seconds ( PubMed ID: 17408666 )

Structure

  • Disulfide bond:  NA
  • Structure ID:  NA

  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
    •    hor000431_AF2.pdbhor000431_ESM.pdb

Physical Information

Mass: 101908 Formula: C43H63N11O10
Absent amino acids: CDEHIKMNQSTVW Common amino acids: A
pI: 9.35 Basic residues: 1
Polar residues: 2 Hydrophobic residues: 4
Hydrophobicity: 30 Boman Index: -260
Half-Life / Aliphatic Index: 4.4 hour Aliphatic Index: 73.75
Instability Index: 6242.5 Extinction Coefficient cystines: 1490
Absorbance 280nm: 212.86

Literature

  • PubMed ID:  19523386##17408666
  • Title:  Characterization of the Carcinus Maenas Neuropeptidome by Mass Spectrometry and Functional Genomics